SSB (N-Term) 抗體

抗原
SSB
別名 SS-B, LARP3, La, lab1, larp3, ssb, Mt-SSB, MtSSB, Ssbp1
抗原表位
 其他選擇N-Term
適用
 其他選擇Murine, Rat ((Rattus)), Dog (Canine), Bovine, Human
宿主
 其他選擇Rabbit
克隆類型
多克隆
標(biāo)記
 其他選擇非結(jié)合性
應(yīng)用范圍
 其他選擇Immunohistochemistry (IHC), Western Blotting (WB)
[Pubmed] 1 reference available
規(guī)格 50 μg
發(fā)貨至 中國 (更改)
發(fā)貨時間 9至12個工作日

SSB (N-Term) 抗體

產(chǎn)品細節(jié)

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免疫原 Synthetic peptide directed towards the N terminal of human SSB
序列 ISEDKTKIRR SPSKPLPEVT DEYKNDVKNR SVYIKGFPTD ATLDDIKEWL
預(yù)測反應(yīng) Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Rat : 100 %, Pig : 90 %
產(chǎn)品特性 This is a rabbit polyclonal antibody against SSB. It was validated on Western Blot and immunohistochemistry.
純化方法 Affinity Purified

SSB (N-Term) 抗體目標(biāo)詳細情況

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背景 SSB is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. SSB protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus.La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III (see MIM 606007)-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus (SLE, MIM 152700) (Teplova et al., 2006).
分子量 45 kDa
基因ID 6741
NCBI Accession NP_003133, NM_003142
UniProt P05455
研究領(lǐng)域 Chromatin and Nuclear Signaling, DNA/RNA

SSB (N-Term) 抗體使用細節(jié)

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應(yīng)用備注 Optimal working dilutions should be determined experimentally by the investigator.
說明

Antigen size: 408 AA

限制 For Research Use only

貯存及處理

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狀態(tài) Lyophilized
溶解方式 Add 50 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項 Avoid repeated freeze-thaw cycles.
儲存條件 -20 °C
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