Exosome Component 6 (EXOSC6) (N-Term) 抗體

抗原

Exosome Component 6 (EXOSC6)
別名 exosc6, RAR-gamma, id:ibd1130, wu:fe17d05, zgc:110071, EAP4, MTR3, Mtr3p, hMtr3p, p11, 2610510N21Rik, C76919, Mtr3
抗原表位
 其他選擇N-Term
適用
 其他選擇Murine, Rat ((Rattus)), Dog (Canine), Bovine, Zebrafish (Danio rerio), Human
宿主
 其他選擇Rabbit
克隆類型
多克隆
標記
 其他選擇非結(jié)合性
應(yīng)用范圍
 其他選擇Western Blotting (WB)
[Pubmed] 1 reference available
規(guī)格 50 μg
發(fā)貨至 中國 (更改)
發(fā)貨時間 9至12個工作日

Exosome Component 6 (EXOSC6) (N-Term) 抗體

產(chǎn)品細節(jié)

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免疫原 Synthetic peptide directed towards the N terminal of human EXOSC6
序列 LYAADEEEAP GTRDPTRLRP VYARAGLLSQ AKGSAYLEAG GTKVLCAVSG
預(yù)測反應(yīng) Bovine : 100 %, Rat : 100 %
產(chǎn)品特性 This is a rabbit polyclonal antibody against EXOSC6. It was validated on Western Blot using a cell lysate as a positive control.
純化方法 Affinity Purified

Exosome Component 6 (EXOSC6) (N-Term) 抗體目標詳細情況

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別名 EXOSC6
背景 EXOSC6 constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.
分子量 30 kDa
基因ID 118460
NCBI Accession NM_058219, NP_478126
UniProt Q5RKV6
研究領(lǐng)域 Chromatin and Nuclear Signaling, DNA/RNA

Exosome Component 6 (EXOSC6) (N-Term) 抗體使用細節(jié)

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應(yīng)用備注 Optimal working dilutions should be determined experimentally by the investigator.
說明

Antigen size: 272 AA

限制 For Research Use only

貯存及處理

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狀態(tài) Lyophilized
溶解方式 Add 50 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項 Avoid repeated freeze-thaw cycles.
儲存條件 -20 °C
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