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IL2RB抗體

抗原
Interleukin 2 Receptor, beta (IL2RB)
別名 IL2RB, il-2rb, CD122, IL15RB, P70-75, IL2RBC, IL-15Rbeta, IL15Rbeta, Il-2/15Rbeta, Il-2Rbeta, p70
適用
其他選擇 Murine
Murine(184),Human (102),Rat ((Rattus)) (68),Bovine (24),Chicken (12),Pig (Porcine) (12),Monkey (2)
宿主
其他選擇 Rat
Rat(125),Rabbit (84),Mouse (40)
克隆類型 (克隆位點(diǎn))
單克隆 (TM-BETA 1)
標(biāo)記
其他選擇 PE
Biotin(32),FITC (32),PE (29),APC (5),Alexa Fluor 350 (2),Alexa Fluor 488 (2),Alexa Fluor 555 (2),Alexa Fluor 647 (2),Cy3 (2),Cy5 (2),Cy5.5 (2),Cy7 (2),HRP (2),Allophycocyanin (1),DyLight 488 (1),DyLight 550 (1),DyLight 594 (1),DyLight 650 (1),DyLight 755 (1),PerCP (1)
應(yīng)用范圍
其他選擇 Flow Cytometry (FACS)
Flow Cytometry (FACS)(153),Western Blotting (WB) (71),ELISA (41),Immunoprecipitation (IP) (37),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (20),Immunohistochemistry (IHC) (20),Functional Studies (Func) (12),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (12),Immunofluorescence (IF) (11),Immunocytochemistry (ICC) (5),Immunoassay (IA) (4),Neutralization (Neut) (4),Immunohistochemistry (Frozen Sections) (IHC (fro)) (2),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (1)
[Pubmed] 1 reference available
規(guī)格 25 tests
發(fā)貨至 中國 (更改)
發(fā)貨時(shí)間 29至35個(gè)工作日

IL2RB抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 Cells from murine IL-2RB+ transformant TART-mBeta. Lymph node (cells from immunised Sprague Dawley rats were fused with cells of the mouse PA1 myeloma cell line.
克隆位點(diǎn) TM-BETA 1
亞型 IgG2b
特異性 This antibody recognises the CD122 cell surface glycoprotein, a 75-85 kDa molecule also known as interleukin-2 receptor (IL-2R) beta chain. Clone TM-beta 1 is reported to block IL-2 high affinity binding to the IL-2R beta receptor. We recommend the use of SM2224LE for this purpose.
純化方法 Affinity Chromatography on Protein G

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 CD122 / IL2RB
背景 In mouse, CD122 is primarily expressed on natural killer (NK) cells and at lower levels on lymphocyte subsets, monocytes and macrophages. CD122 can associate with the IL-2R alpha chain (CD25) and CD132 to form a functional high affinity receptor complex that binds IL-2. CD132/CD122 heterodimers can also be formed which bind IL-2 with intermediate affinity. IL-2 binding to the IL-2R is important in the generation and differentiation of T lymphocytes and NK cells.Synonyms: IL-2 receptor subunit beta, IL2 Receptor beta, Interleukin-2 receptor subunit beta, P70-75
基因ID 16185
NCBI Accession NP_032394
UniProt P16297
研究領(lǐng)域 CD Antigens, Surface Receptors of Immune Cells

使用細(xì)節(jié)

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使用細(xì)節(jié)

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應(yīng)用備注 Flow Cytometry (Neat-1/5): Use 10 μL of the suggested working dilution to label 106 cells in 100?μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 For Research Use only

貯存及處理

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貯存及處理

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溶解方式 Restore with 1.0?mL distilled water
濃度 0.1 mg/mL
緩沖液 PBS,?pH 7.4 containing 0.09?% Sodium Azide and 1?% Bovine Serum Albumin.
儲存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事項(xiàng) This product is photosensitive and should be protected from light
儲存條件 4 °C
儲存方法 Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE!

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