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UGT1A1抗體

抗原
UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)
別名 BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT 1-1, UGT1, UGT1A, Gnt1, UGT1A01, Udpgt-1a, UgtBr1, Udpgt, Ugt1
抗原表位
其他選擇 N-Term, AA 65-90
N-Term(10),AA 64-91 (7),Middle Region (2),AA 247-533 (1),AA 60-168 (1),AA 65-90 (1),Internal Region (1)
適用
其他選擇 Human
Human(20),Murine (2),Rat ((Rattus)) (2),Dog (Canine) (1),Rabbit (1)
宿主
其他選擇 Rabbit
Rabbit(19),Goat (1)
克隆類型 (克隆位點(diǎn))
多克隆 (RB22607)
標(biāo)記
其他選擇 非結(jié)合性
APC(1),Alkaline Phosphatase (AP) (1),Biotin (1),FITC (1),HRP (1),PE (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
Western Blotting (WB)(20),Immunohistochemistry (IHC) (10),ELISA (7),Immunocytochemistry (ICC) (6),Immunofluorescence (IF) (4),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1)
[Pubmed] 1 reference available
規(guī)格 400 μL
發(fā)貨至 中國(guó) (更改)
發(fā)貨時(shí)間 9至13個(gè)工作日

UGT1A1抗體

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產(chǎn)品細(xì)節(jié)

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免疫原 This UGT1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-90 AA from the N-terminal region of human UGT1A1.
克隆位點(diǎn) RB22607
亞型 Ig
特異性 This UGT1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-91 amino acids from the N-terminal region of human UGT1A1.
純化方法 This antibody is purified through a protein A column, followed by peptide affinity purification.

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目標(biāo)詳細(xì)情況

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別名 UGT1A1
背景 This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome.
Synonyms: UDP-glucuronosyltransferase 1-1,54658,GNT1, UGT1
分子量 59591 DA
基因ID 54658
NCBI Accession NP_000454
UniProt P22309
研究領(lǐng)域 Cell Signaling, Cell Structure, Protein Modifications

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應(yīng)用備注 WB = 1:1000, IF = 1:10-50, IHC = 1:10-50
限制 For Research Use only

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狀態(tài) Liquid
濃度 0.42 mg/mL
緩沖液 PBS with 0.09 % (W/V) sodium azide
儲(chǔ)存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲(chǔ)存條件 4 °C/-20 °C
儲(chǔ)存方法 UGT1A1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
有效期 6 months

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