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ATF3抗體

抗原
Activating Transcription Factor 3 (ATF3)
別名 zgc:55526, ATF3, LRG-21, LRF-1, LRFI, atf-3
抗原表位
其他選擇 Middle Region
C-Term(14),AA 1-181 (7),AA 113-130 (6),AA 139-168 (5),N-Term (5),AA 1-182 (3),AA 140-168 (3),AA 1-90 (1),AA 131-180 (1),Asn159 (1),Internal Region (1)
適用
其他選擇 Rat ((Rattus)), Murine, Dog (Canine), Bovine, Xenopus laevis, Human, Chicken
Human(71),Murine (28),Rat ((Rattus)) (26),Chicken (13),Bovine (13),Dog (Canine) (13),Mammalian (1)
宿主
其他選擇 Rabbit
Rabbit(54),Mouse (14),Sheep (4)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
FITC(2),APC (1),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),Biotin (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),HRP (1),PE (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB)
Western Blotting (WB)(54),ELISA (32),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Flow Cytometry (FACS) (9),Immunohistochemistry (IHC) (9),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8),Immunoprecipitation (IP) (4),Enzyme Immunoassay (EIA) (3),Dot Blot (DB) (2),Immunoassay (IA) (2),Immunocytochemistry (ICC) (2),RNA Interference (RNAi) (2),Fluorescence Microscopy (FM) (1),Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (1),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (1)
[Pubmed] 1 reference available
規(guī)格 50 μg
發(fā)貨至 中國(guó) (更改)
發(fā)貨時(shí)間 9至12個(gè)工作日

ATF3抗體

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 Synthetic peptide directed towards the middle region of human ATF3
序列 PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK
預(yù)測(cè)反應(yīng) Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Human : 100 %, Rabbit : 90 %, Rat : 90 %, African clawed frog : 90 %, Mouse : 80 %
產(chǎn)品特性 This is a rabbit polyclonal antibody against ATF3. It was validated on Western Blot using a cell lysate as a positive control.
純化方法 Affinity Purified

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

顯示 隱藏
別名 ATF3
背景 This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF3 represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.
分子量 20 kDa
基因ID 467
NCBI Accession NM_001674, NP_001665
UniProt P18847
研究領(lǐng)域 Cancer, Transcription Factors

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應(yīng)用備注 Optimal working dilutions should be determined experimentally by the investigator.
說明

Antigen size: 181 AA

限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Lyophilized
溶解方式 Add 50 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項(xiàng) Avoid repeated freeze-thaw cycles.
儲(chǔ)存條件 -20 °C
儲(chǔ)存方法 For longer periods of storage, store at -20 °C

抗原
Activating Transcription Factor 3 (ATF3)
別名 zgc:55526, ATF3, LRG-21, LRF-1, LRFI, atf-3
抗原表位
其他選擇 Middle Region
C-Term(14),AA 1-181 (7),AA 113-130 (6),AA 139-168 (5),N-Term (5),AA 1-182 (3),AA 140-168 (3),AA 1-90 (1),AA 131-180 (1),Asn159 (1),Internal Region (1)
適用
其他選擇 Rat ((Rattus)), Murine, Dog (Canine), Bovine, Xenopus laevis, Human, Chicken
Human(71),Murine (28),Rat ((Rattus)) (26),Chicken (13),Bovine (13),Dog (Canine) (13),Mammalian (1)
宿主
其他選擇 Rabbit
Rabbit(54),Mouse (14),Sheep (4)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
FITC(2),APC (1),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),Biotin (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),HRP (1),PE (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB)
Western Blotting (WB)(54),ELISA (32),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Flow Cytometry (FACS) (9),Immunohistochemistry (IHC) (9),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8),Immunoprecipitation (IP) (4),Enzyme Immunoassay (EIA) (3),Dot Blot (DB) (2),Immunoassay (IA) (2),Immunocytochemistry (ICC) (2),RNA Interference (RNAi) (2),Fluorescence Microscopy (FM) (1),Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (1),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (1)
[Pubmed] 1 reference available
規(guī)格 50 μg
發(fā)貨至 中國(guó) (更改)
發(fā)貨時(shí)間 9至12個(gè)工作日

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[anti-Activating Transcription Factor 3 (ATF3) (Middle Region) antibody]

產(chǎn)品編號(hào) ABIN405094
2,993.68 ￥
(含稅, 含運(yùn)費(fèi))
請(qǐng)求報(bào)價(jià) 來自 聯(lián)世生物科技（上海）有限公司 （本地經(jīng)銷商）
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中國(guó) 上海 200060
安遠(yuǎn)路518號(hào)
寶華城市晶典大廈
1203室
聯(lián)世生物科技（上海）有限公司
+86-21-6208-5950
傳真 +86-21-6208-9071
info@global-biotech.cn
www.global-biotech.cn

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 Synthetic peptide directed towards the middle region of human ATF3
序列 PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK
預(yù)測(cè)反應(yīng) Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Human : 100 %, Rabbit : 90 %, Rat : 90 %, African clawed frog : 90 %, Mouse : 80 %
產(chǎn)品特性 This is a rabbit polyclonal antibody against ATF3. It was validated on Western Blot using a cell lysate as a positive control.
純化方法 Affinity Purified

目標(biāo)詳細(xì)情況

引用 圖像 貯存及處理 使用細(xì)節(jié) 回頁(yè)首

目標(biāo)詳細(xì)情況

顯示 隱藏
別名 ATF3
背景 This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF3 represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.
分子量 20 kDa
基因ID 467
NCBI Accession NM_001674, NP_001665
UniProt P18847
研究領(lǐng)域 Cancer, Transcription Factors

使用細(xì)節(jié)

引用 圖像 貯存及處理 目標(biāo)詳細(xì)情況 回頁(yè)首

使用細(xì)節(jié)

顯示 隱藏
應(yīng)用備注 Optimal working dilutions should be determined experimentally by the investigator.
說明

Antigen size: 181 AA

限制 For Research Use only

貯存及處理

引用 圖像 使用細(xì)節(jié) 目標(biāo)詳細(xì)情況 回頁(yè)首

貯存及處理

顯示 隱藏
狀態(tài) Lyophilized
溶解方式 Add 50 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項(xiàng) Avoid repeated freeze-thaw cycles.
儲(chǔ)存條件 -20 °C
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