PCDHGC4 抗體 返回列表頁

PCDHGC4 抗體

抗原
Protocadherin gamma Subfamily C, 4 (PCDHGC4)
別名 PCDH-GAMMA-C4
抗原表位
其他選擇 N-Term
N-Term(8),AA 264-291 (7),AA 1-208 (1),AA 288-553 (1),AA 380-642 (1),AA 52-141 (1)
適用
其他選擇 Murine, Rat ((Rattus)), Zebrafish (Danio rerio), Fruit Fly (Drosophila melanogaster), Human
Human(27),Murine (14),Dog (Canine) (13),Rat ((Rattus)) (13)
宿主
其他選擇 Rabbit
Rabbit(26),Mouse (1)
克隆類型
多克隆
標記
其他選擇 非結合性
Biotin(2),FITC (2),HRP (2),PE (2),APC (1),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1)
應用范圍
其他選擇 Western Blotting (WB)
Western Blotting (WB)(17),Flow Cytometry (FACS) (11),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),ELISA (9),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4),Immunohistochemistry (IHC) (2)
[Pubmed] 1 reference available
規(guī)格 50 μg
發(fā)貨至 中國 (更改)
發(fā)貨時間 9至12個工作日

PCDHGC4 抗體

產(chǎn)品細節(jié)

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產(chǎn)品細節(jié)

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免疫原 Synthetic peptide directed towards the N terminal of human PCDHGC4
序列 VKKRSDGSLV PELLLEKPLD REKQSDYRLV LTAVDGGNPP RSGTAELRVS
預測反應 Human : 100 %, Mouse : 100 %
產(chǎn)品特性 This is a rabbit polyclonal antibody against PCDHGC4. It was validated on Western Blot using a cell lysate as a positive control.
純化方法 Affinity Purified

目標詳細情況

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目標詳細情況

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別名 PCDHGC4
背景 PCDHGC4 is a single-pass type I membrane protein. It contains 6 cadherin domains.PCDHGC4 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
分子量 98 kDa
基因ID 56098
NCBI Accession NM_018928, NP_061751
UniProt Q9Y5F7
研究領域 Signaling

使用細節(jié)

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使用細節(jié)

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應用備注 Optimal working dilutions should be determined experimentally by the investigator.
說明

Antigen size: 938 AA

限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Lyophilized
溶解方式 Add 50 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項 Avoid repeated freeze-thaw cycles.
儲存條件 -20 °C
儲存方法 For longer periods of storage, store at -20 °C

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