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當(dāng)前位置:上海信裕生物科技有限公司>>抗體>>一抗>> CST3抗體
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抗原
Cystatin C (CST3)
別名 armd11, fb51d07, wu:fb24g06, wu:fb51d07, wu:fc55f03, zgc:136227, ARMD11, CysC, CYSC
適用
其他選擇 Human
Human(241),Murine (45),Rat ((Rattus)) (32),Bovine (5),Chicken (3),Monkey (1),Rabbit (1)
宿主
其他選擇 Mouse
Rabbit(131),Mouse (110),Goat (44),Sheep (5),Rat (2)
克隆類型
單克隆
標(biāo)記
其他選擇 非結(jié)合性
Biotin(17),FITC (15),HRP (13),APC (1),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),Biotin,His tag (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),Magnetic Particles (1),PE (1),Sepharose (1)
應(yīng)用范圍
其他選擇 ELISA, Western Blotting (WB)
ELISA(205),Western Blotting (WB) (160),Immunohistochemistry (IHC) (48),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (32),Immunocytochemistry (ICC) (17),Immunoassay (IA) (12),Immunohistochemistry (Frozen Sections) (IHC (fro)) (11),Immunoprecipitation (IP) (11),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Protein Assay (PrA) (8),Enzyme Immunoassay (EIA) (7),Flow Cytometry (FACS) (5),ELISA (Detection) (4),Immunofluorescence (IF) (4),ELISA (Capture) (2),Latex enhanced turbidimetric Immunoassay (LETIA) (2),Radioimmunoassay (RIA) (2),Dot Blot (DB) (1),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (1),Labeling (Lbl) (1),Neutralization (Neut) (1)
[Pubmed] 17 references available
規(guī)格 100 μg
發(fā)貨至 中國 (更改)
發(fā)貨時間 11至15個工作日
CST3抗體
產(chǎn)品細(xì)節(jié)
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產(chǎn)品細(xì)節(jié)
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免疫原 Recombinant Human Cystatin C protein
亞型 IgG2b
特異性 Specific for Human Cystatin C denatured and native forms
純化方法 Caprylic Acid Ammonium Sulfate Precipitation
目標(biāo)詳細(xì)情況
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別名 Cystatin C
背景 Defects in CST3 are the cause of amyloidosis type 6 (AMYL6) [MIM:105150], also known as hereditary cerebral hemorrhage with amyloidosis (HCHWA), cerebral amyloid angiopathy (CAA) or cerebroarterial amyloidosis Icelandic type. AMYL6 is a hereditary generalized amyloidosis due to cystatin C amyloid deposition. Cystatin C amyloid accumulates in the walls of arteries, arterioles, and sometimes capillaries and veins of the brain, and in various organs including lymphoid tissue, spleen, salivary glands, and seminal vesicles. Amyloid deposition in the cerebral vessels results in cerebral amyloid angiopathy, cerebral hemorrhage and premature stroke. Cystatin C levels in the cerebrospinal fluid are abnormally low.Genetic variations in CST3 are associated with age-related macular degeneration type 11 (ARMD11) [MIM:611953]. ARMD is a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane.
Synonyms: CysC,Cystatin-3,Gamma-trace,Neuroendocrine basic polypeptide,Post-gamma-globulin
UniProt P01034
研究領(lǐng)域 Cardiovascular, Atherosclerosis, Apoptosis/Necrosis, Serum/Plasma Proteins
使用細(xì)節(jié)
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應(yīng)用備注 Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the investigator.
說明
Other species are not tested. Please decide the specificity by homology
限制 For Research Use only
貯存及處理
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貯存及處理
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狀態(tài) Liquid
緩沖液 0.03 % Proclin 300, 50 % Glycerol, 0.01 M PBS, pH 7.4
儲存液 ProClin
注意事項(xiàng) This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
注意事項(xiàng) Avoid freeze and thaw cycles.
儲存條件 -20 °C
儲存方法 Shipped at 4 °C Upon delivery aliquot and store at -24 °C or -84 °C.
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