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抗原
Tumor Necrosis Factor (TNF)
別名 TNF, tnf, dif, tnfa, xtnf, TNF-a, tnfsf2, tnf-alpha, TNF-alpha, DIF, TNFA, TNFSF2, TNFalpha, Tnfa, Tnfsf1a, RATTNF, TNFa, cTNF, TNF-ALPHA, Cachectin, Tnf-alpha, tnfa-like
適用
其他選擇 Human
Human(467),Murine (202),Rat ((Rattus)) (98),Bovine (35),Pig (Porcine) (35),Dog (Canine) (32),Monkey (22),Guinea Pig (19),Sheep (Ovine) (10),Horse (Equine) (8),Rhesus Monkey (8),Rabbit (5),Wild boar (Sus scrofa) (5),Baboon (4),Chicken (4),Zebrafish (4),Ferret (2),Non-Human Primate (2),Cat (1),Hamster (1)
宿主
其他選擇 Mouse
Mouse(334),Rabbit (273),Rat (86),Goat (23),Hamster (17),Armenian Hamster (13),Sheep (8),Chicken (4),Guinea Pig (4)
克隆類型
單克隆
標記
其他選擇 非結(jié)合性
Biotin(80),FITC (50),PE (32),HRP (10),APC (8),Alexa Fluor 488 (4),Cy5 (4),PE,Cy7 (3),Alexa Fluor 350 (2),Alexa Fluor 555 (2),Alexa Fluor 647 (2),Allophycocyanin (2),Cy3 (2),Cy5.5 (2),Cy7 (2),Cy7,PE (2),EFluor 450 (2),His tag,GST tag (2),PerCP (2),Alkaline Phosphatase (AP) (1),DyLight 488 (1),DyLight 550 (1),DyLight 594 (1),DyLight 633 (1),DyLight 650 (1),DyLight 680 (1),DyLight 755 (1),DyLight 800 (1),FITC,His tag (1),Magnetic Particles (1),Sepharose (1)
應用范圍
其他選擇 ELISA, Western Blotting (WB)
Western Blotting (WB)(394),ELISA (379),Flow Cytometry (FACS) (197),Immunohistochemistry (IHC) (118),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (91),Immunohistochemistry (Frozen Sections) (IHC (fro)) (83),Enzyme Immunoassay (EIA) (67),Functional Studies (Func) (64),Neutralization (Neut) (61),Immunocytochemistry (ICC) (57),Immunoprecipitation (IP) (55),Immunofluorescence (IF) (32),Radioimmunoassay (RIA) (29),Blocking Antibody (Inhibition) (21),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (20),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (19),ELISpot (18),ELISA (Capture) (5),ELISA (Detection) (3),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3),Intracellular Staining (ICS) (3),Dot Blot (DB) (2),Immunoassay (IA) (2),Protein Assay (PrA) (2),Transfected cell culture (TCC) (2),ELISpot (Capture) (1),ELISpot (Detection) (1),In vivo Cytokine Capture Assay (IVCCA) (1)
[Pubmed] 5 references available
規(guī)格 100 μg
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TNF 抗體
產(chǎn)品細節(jié)
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免疫原 Recombinant Human TNF alpha protein
亞型 IgG2a
特異性 Specific for denatured forms
純化方法 Caprylic Acid Ammonium Sulfate Precipitation
目標詳細情況
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別名 TNF alpha
背景 Tumor necrosis factor alpha (TNF-α), also known as cachectin and TNFSF1A, is the prototypic cytokine of the the TNF superfamily. It is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF-α is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). Two receptors mediating the TNF-α function have been identified, the ubiquitous TNF RI from which most signaling are derived, and the hematopoietic cell-restricted TNF RII. TNF-α has been implicated in the pathogenesis of a variety of human diseases including autoimmune diseases, insulin resistance, and cancer.
Synonyms: TNF-a,Cachectin,Tumor necrosis factor ligand superfamily member 2
UniProt P01375
研究領域 Cardiovascular, Atherosclerosis, Growth Factors, Innate Immunity, Cytokines, Receptors, Immunology, Inflammation, Cancer, Virology
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應用備注 Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the investigator.
說明
Other species are not tested. Please decide the specificity by homology
限制 For Research Use only
貯存及處理
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狀態(tài) Liquid
緩沖液 0.03 % Proclin 300, 50 % Glycerol, 0.01 M PBS, pH 7.4
儲存液 ProClin
注意事項 This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
注意事項 Avoid freeze and thaw cycles.
儲存條件 -20 °C
儲存方法 Shipped at 4 °C Upon delivery aliquot and store at -24 °C or -84 °C.
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